This is the projects page for the Optogenetics and Neural Engineering (ONE) Core, affiliated with the School of Medicine, located on the Anschutz Medical Campus.

Our mission is to support neuroscience and other biomedical research by making engineering resources available and accessible to the research community.

See the links at the left for examples of previous projects on which we have worked, and support we provide. We are a part of the NeuroTechnology Center and we work closely with the Scientific Computing Core and Neuroscience Machine Shop. Many of the labs we work with are in the Neuroscience Program.

Please email us with any project ideas, questions, comments, or requests for quotes.




Andrew Scallon is the Manager of the ONE Core. With an education in Mechanical Engineering and Neuroscience Engineering from the University of Wisconsin, Madison, he is an engineering resource for your research. He offers a diverse background in Optics, Mechanical, Biological, Hardware, and Software Engineering and an eagerness to assist you in your research.

Nathan Baker is a Professional Research Assistant in the ONE Core. He received a Neuroscience education at Vanderbilt University, and has developed a key skill-set in programming languages, including MATLAB and Python, during his time at the Anschutz Medical Campus. He applies his background in in-vivo and in-vitro to the broad breadth of engineering performed by the ONE Core.

Gidon Felsen is the Director of the ONE Core. His lab is investigating how sensory representations are transformed into plans for motor output and uses electrophysiological, behavioral, pharmacological, molecular, and computational methods of study. Current studies focus on the distinct roles played by several interconnected subcortical brain regions: The superior colliculus, pedunculopontine tegmental nucleus,and substantia nigra pars reticulata.

Abigail Person is the Co-Director of the ONE Core. Her laboratory studies the contribution of the cerebellum to motor control, focusing on circuit mechanisms that support smooth, precise movement. By combining physiological, optogenetic, anatomical, and behavioral methods, she aims to address how cerebellar circuitry makes movements precise.


Aidan Armstrong was a Professional Research Assistant in the ONE Core. His Biomedical Engineering education at SUNY Buffalo provided him with a background in MRI and optical imaging techniques. He applied his broad science and engineering skill sets to a wide variety of projects within the ONE Core.

Pictures credited to Dailey Nettles.

Additional thanks to the ONE Core Steering Committee

Principle Investigators ​Department
​Achim Klug ​Physiology and Biophysics​
​Tim Lei​ ​Electrical Engineering
Chandra Tucker Pharmacology
​Diego Restrepo Cell and Developmental Biology
Doug Shepherd Pharmacology


Please acknowledge the ONE Core in publications resulting from research we supported. Example wording: ““The Optogenetics and Neural Engineering (ONE) Core at the University of Colorado School of Medicine provided engineering support for this research. The ONE Core is part of the NeuroTechnology Center, funded in part by the School of Medicine and by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under award number P30NS048154.”


Please contact the Optogenetics and Neural Engineering Core via email with any questions, comments, or requests for quotes.