Modular auditory decision-making behavioral task designed for intraoperative use in humans
Projects | | Links:
An open-source intraoperative paradigm; behavioral and neural data acquired during awake human brain surgery.
This is a simple and inexpensive Arduino based system for recording behavior intraoperatively. As demonstrated, a patient undergoing Deep Brain Stimulation (DBS) (recording and stimulation) can be asked to discriminate and move to declare a choice between two audio frequency presentations. The movements of the patient can be monitored with this simple and inexpensive Arduino based system and a Wii Nunchuck. This Nunchuck allows the user to move a joystick with their thumbs AND includes a 3-axis accelerometer (perfect for recording tremors!). The movement of the thumb can be restricted with a 3D printed part (forcing the choice to be left or right), and the given MATLAB code will help you interpret your results.
This work was published under Modular auditory decision-making behavioral task designed for intraoperative use in humans, Tekriwal A, Felsen G, and Thompson JA (2018) J Neurosci Methods. 2018 Jul 1;304:162-167. doi: 10.1016/j.jneumeth.2018.05.004. Epub 2018 May 7. More information can be found there and in their GitHub.
ONE Core acknowledgement
Please acknowledge the ONE Core facility in your publications. An appropriate wording would be:
“The Optogenetics and Neural Engineering (ONE) Core at the University of Colorado School of Medicine provided engineering support for this research. The ONE Core is part of the NeuroTechnology Center, funded in part by the School of Medicine and by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under award number P30NS048154.”